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MANAGING DENTAL ANXIETY: INTRANASAL & IV CONSCIOUS SEDATION

At Dental Sedation Solutions, we understand that needle phobia is a profound issue that can have a significant impact on a person's ability to access dental care. Many patients feel helpless or misunderstood, which is why we use intranasal sedation alongside other conscious sedation techniques, including premedication, inhalation sedation and intravenous (IV) sedation, to provide a personalised approach that helps patients feel safe, calm and supported.


To completely avoid the use of needles during the initial stage of your visit, we use a specialised Mucosal Atomization Device (MAD). As pictured on the left, this device fits gently at the entrance of your nostril and converts the liquid sedative into a fine, gentle mist. This needle-free technique is designed to help you feel calm and relaxed before any procedures.


Our Sedation Techniques

Learn more about the conscious sedation techniques we use as part of your personalised treatment plan:

  • Premedication
  • Inhalation Sedation
  • Intravenous (IV) Sedation

What is Intranasal Conscious Sedation?

Intranasal sedation is a safe and effective technique in which a fine spray of the sedative Midazolam is administered directly into your nose.


  • How it works: The sedative is rapidly absorbed through your nasal lining.
  • The Timeline: It typically takes just 2 to 10 minutes to take effect.
  • The Result: You will quickly begin to feel relaxed, drowsy, and calm.
    Transition to IV Sedation: Once this initial conscious sedation has taken effect, our team can gently insert a cannula (a small plastic tube) into a vein in your hand or arm. We then transition to intravenous (IV) sedation to maintain a suitable level of conscious sedation throughout your dental procedure.

Important Safety Note:

This is a form of conscious sedation. You will remain conscious and able to respond to simple instructions throughout your entire appointment. Sedation will be carried out by a Consultant Anaesthetist. 

Who is Intranasal Sedation For?

This specialised service is specifically designed for:

  • Severe Needle Phobics: Patients who experience intense anxiety or find themselves unable to tolerate a cannula insertion while fully conscious.
  • Medical Anxiety: Individuals who find medical environments, injections, or blood tests highly stressful.
  • Special Care Needs: It provides a compassionate, supportive option for patients with severe learning disabilities or movement disorders who might otherwise struggle to cope with dental treatment.

what to expect

1. Pre-Appointment Preparation & EMLA Cream

Before your appointment, we can discuss appropriate pre-medication options to help manage your anxiety before you even arrive. Additionally, we have EMLA cream (a prescription-strength numbing cream, shown in the photo on the right-hand side), which you apply to your hand or arm before the appointment to ensure the skin is fully numbed before the cannula is inserted.



2. Delivered by a Consultant Anaesthetist

Your safety is our absolute priority. Your intranasal and IV conscious sedation is planned and delivered directly by our highly experienced Consultant Anaesthetist, ensuring specialist medical supervision and continuous monitoring of your oxygen levels, pulse, breathing, and blood pressure throughout.

3. Needle-Free Initiation

As highlighted above, the initial nasal sedative is delivered using the Mucosal Atomization Device (MAD). This converts the liquid medication into a fine mist for quick, needle-free absorption through the nasal lining.

We tailor your treatment to your specific clinical needs. Other available options include:

  • Local Anaesthesia Only: Treatment is completed with the area numbed by local injections while you are fully awake, without any sedation.
  • Inhalation Sedation: Often referred to as "laughing gas," this involves breathing a mixture of nitrous oxide and oxygen through a nosepiece to promote a light form of relaxation.
  • Oral Sedation: This involves drinking a liquid sedative to help you relax before cannula placement. It is slightly less potent than intranasal sedation and takes longer to take effect.
  • General Anaesthesia (GA): This involves being fully unconscious in a hospital operating theatre. GA cannot be offered in a UK dental clinic, and treatment under GA is generally limited to teeth extractions.


We want you to be fully informed about your care. Below is an overview of the key points covered in our patient consent forms:


  • Anxiety Reduction: Helps you feel relaxed, calm, and able to tolerate the placement of a cannula.
  • Drowsy Relaxation: You remain fully conscious but feel incredibly relaxed and comfortable during your treatment.
  • Temporary Amnesia: Midazolam naturally causes a temporary reduction in your memory of the procedure. Many patients remember very little, if anything, about their dental treatment.


While conscious sedation is highly safe when administered by medical professionals, some minor and temporary side effects can occur:


  • Nasal Sensations: The intranasal spray may cause a temporary stinging sensation or discomfort inside the nose (to minimise this, it is mixed with a numbing agent). It may also cause sneezing, a temporary unpleasant taste, or a minor nosebleed.
  • Slowing of Breathing: Sedatives can slightly slow your breathing. Our Consultant Anaesthetist continuously monitors your breathing and oxygen levels, and supplemental oxygen is always immediately available if needed.
  • Cannula Bruising: You may experience minor bruising or discomfort at the cannula site on your hand or arm.
  • Varied Effectiveness: Sedation may not be fully effective in a small number of patients (for example, due to medication tolerance). If adequate conscious sedation cannot be safely achieved, the procedure may be stopped and reviewed.


Using Midazolam intranasally is considered an “off-licence” use. This simply means it is being administered in a different way than its original product license. Dentists and doctors are legally and professionally permitted to use medicines in this way when they judge it to be safe, clinically appropriate, and highly effective. Intranasal Midazolam is a widely used technique in dentistry with an excellent safety record.


Patient Information leaflet

Intranasal Sedation for Patients (pdf)Download

More Sedation Management & Options

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Oral Premedication

Find out more

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Intravenous (IV) Sedation

Overcome your barriers

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Inhalation Sedation

Not just for children

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Special Care Dentistry

Every patient is welcome

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Clinical Hypnotherapy

Find out more

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Dental Treatments

With or without sedation

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Website last updated on 29 July 2026 at 18:00

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